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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
17.5 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hnf4a  hepatic nuclear factor 4, alpha   (Synonyms: Hnf4, HNF-4, HNF4 alpha, MODY1, Nr2a1, Nuclear receptor 2A1, Tcf14, Tcf4)
Results  Reference
1J:231303 Cordi S, Godard C, Saandi T, Jacquemin P, Monga SP, Colnot S, Lemaigre FP, Role of beta-catenin in development of bile ducts. Differentiation. 2016 Jan-Mar;91(1-3):42-9
1*J:124920 Garrison WD, Battle MA, Yang C, Kaestner KH, Sladek FM, Duncan SA, Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology. 2006 Apr;130(4):1207-20
1*J:192058 Jonckheere N, Vincent A, Franquet-Ansart H, Witte-Bouma J, Korteland-van Male A, Leteurtre E, Renes IB, Van Seuningen I, GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells. Biochim Biophys Acta. 2012 Aug;1819(8):869-76
1J:240786 Lee DH, Park JO, Kim TS, Kim SK, Kim TH, Kim MC, Park GS, Kim JH, Kuninaka S, Olson EN, Saya H, Kim SY, Lee H, Lim DS, LATS-YAP/TAZ controls lineage specification by regulating TGFbeta signaling and Hnf4alpha expression during liver development. Nat Commun. 2016 Jun 30;7:11961
1*J:170660 Matsuo A, Yoshida T, Yasukawa T, Miki R, Kume K, Kume S, Epiplakin1 is expressed in the cholangiocyte lineage cells in normal liver and adult progenitor cells in injured liver. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):255-62
1J:329932 Minati MA, Assi M, Libert M, Cordi S, Lemaigre F, Jacquemin P, KRAS protein expression becomes progressively restricted during embryogenesis and in adulthood. Front Cell Dev Biol. 2022;10:995013
1J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310
1*J:130176 Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I, Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas. Gene Expr Patterns. 2008 Jan;8(2):96-106
1J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498
1J:115933 Suh JM, Yu CT, Tang K, Tanaka T, Kodama T, Tsai MJ, Tsai SY, The expression profiles of nuclear receptors in the developing and adult kidney. Mol Endocrinol. 2006 Dec;20(12):3412-20
1J:114400 Yamasaki H, Sada A, Iwata T, Niwa T, Tomizawa M, Xanthopoulos KG, Koike T, Shiojiri N, Suppression of C/EBP{alpha} expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression. Development. 2006 Nov;133(21):4233-43

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory